Intravital microscopy of subpleural alveoli via transthoracic endoscopy
نویسندگان
چکیده
منابع مشابه
Intravital microscopy of subpleural alveoli via transthoracic endoscopy.
Transfer of too high mechanical energy from the ventilator to the lung's alveolar tissue is the main cause for ventilator-induced lung injury (VILI). To investigate the effects of cyclic energy transfer to the alveoli, we introduce a new method of transthoracic endoscopy that provides morphological as well as functional information about alveolar geometry and mechanics. We evaluate the new endo...
متن کاملIntravital microscopy
Intravital microscopy is an extremely powerful tool that enables imaging several biological processes in live animals. Recently, the ability to image subcellular structures in several organs combined with the development of sophisticated genetic tools has made possible extending this approach to investigate several aspects of cell biology. Here we provide a general overview of intravital micros...
متن کاملIntravital microscopy
In principle, there is little difference between conventional microscopy methods and intravital microscopy; in practice, however, there are significant differences in the way images are acquired and processed and a number of unusual features are associated with the microscope mechanics and other accessories. This note describes the approaches that we have developed over the last few years at GC...
متن کاملHigh-Resolution Intravital Microscopy
Cellular communication constitutes a fundamental mechanism of life, for instance by permitting transfer of information through synapses in the nervous system and by leading to activation of cells during the course of immune responses. Monitoring cell-cell interactions within living adult organisms is crucial in order to draw conclusions on their behavior with respect to the fate of cells, tissu...
متن کاملFour-dimensional optical coherence tomography imaging of subpleural alveoli in mice
The development of protective ventilation strategies for patients suffering from life-threatening lung diseases and the promotion of numerical simulation of lung tissue mechanics requires detailed knowledge about the three-dimensional alveolar micro-structure, their dynamics and elastic properties. Subpleural lung tissue can be observed in animal models utilizing optical coherence tomography (O...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2011
ISSN: 1083-3668
DOI: 10.1117/1.3560297